Clinical study on massage combined with external application of Xiaoji powder on Shenque point in treating children's functional constipation with gastrointestinal heat accumulation syndrome / 国际中医中药杂志

Objective@#To evaluate the effect of massage combined with external application of Xiaoji powder on Shenque point in treating children’s functional constipation (FC) of gastrointestinal heat accumulation syndrome.@*Methods@#A total of 88 FC children who met the inclusion criteria were randomly divided into two groups, 44 in each group. The control group was treated with viablebifidobacterium tetrad tablets orally, while the treatment group was treated with massage combined with external application of Xiaoji powder on Shenque point. Both groups were treated for 18 days. Before and after treatment, TCM syndromes were scored from the main symptoms and secondary symptoms to evaluate the clinical efficacy.@*Results@#The effective rate was 93.2% (41/44) in the treatment group and 65.9% (29/44) in the control group. There were significant differences between the two groups (χ2=9.058, P=0.004). After treatment, the scores of main symptoms (3.8 ± 0.6) and minor symptoms (1.7 ± 0.4) in the treatment group were significantly lower than those in the control group (6.8 ± 1.3) and (3.1 ± 0.4) (t=13.899, 16.417, respectively, P<0.05).@*Conclusions@#Massage combined with external application of Xiaoji powder on Shenque point can improve the constipation symptoms and clinical efficacy of children suffering from FC of gastrointestinal heat accumulation syndrome.

Clinical study on treatment of cancerous abdominal pain by traditional Chinese medicine hot-ironing analgesic package at Shenque point combined with abdominal massage therapy / 国际中医中药杂志

Objective@#To observe the effect of traditional Chinese medicine hot-ironing therapy at Shenque point on cancerous abdominal pain in advanced malignant tumors.@*Methods@#Forty patients with cancerous abdominal pain who met the inclusion criteria were randomly divided into two groups, 20 in each group.The control group was treated with traditional Chinese medicine hot-ironing analgesic package at Shenque point, and the treatment group was treated with abdominal massage therapy on the basis of the control group. Both groups were treated continuously for 7 days. The degree of abdominal pain was assessed using a digital assessment scale, and the quality of life was assessed using a quality of life assessment scale. The time to remission of cancerous abdominal pain was observed during the treatment period.@*Results@#After treatment, the NRS scores on the 3rd day (1.9 ± 0.6 vs. 2.4 ± 0.3, t=3.333), 5th day (1.0 ± 0.3 vs. 1.6 ± 0.5, t=4.602), 7th day (1.0 ± 0.6 vs. 2.4 ± 0.7, t=6.791), in the treatment group were significantly lower than those in the control group (P<0.01). The remission time of the treatment group was longer than that of the control group on the 1st, 3rd, 5th and 7th day after treatment, but there was no significant difference between the groups (t values were 0.243, 1.374, 0.185, 0.7284, P>0.05). The body function score in the treatment group (88.6 ± 13.7 vs. 77.0 ± 19.4, t=2.184) was significantly higher than that in the control group (P<0.05).@*Conclusions@#The combination of traditional Chinese medicine hot-ironing package combined with pushing therapy can alleviate the pain level and improve the quality of life of patients with cancerous abdominal pain.

Clinical study on treatment of cancerous abdominal pain by traditional Chinese medicine hot-ironing analgesic package at Shenque point combined with abdominal massage therapy / 国际中医中药杂志

Objective To observe the effect of traditional Chinese medicine hot-ironing therapy at Shenque point on cancerous abdominal pain in advanced malignant tumors. Methods Forty patients with cancerous abdominal pain who met the inclusion criteria were randomly divided into two groups, 20 in each group.The control group was treated with traditional Chinese medicine hot-ironing analgesic package at Shenque point, and the treatment group was treated with abdominal massage therapy on the basis of the control group. Both groups were treated continuously for 7 days. The degree of abdominal pain was assessed using a digital assessment scale, and the quality of life was assessed using a quality of life assessment scale. The time to remission of cancerous abdominal pain was observed during the treatment period. Results After treatment, the NRS scores on the 3rd day (1.9 ± 0.6 vs. 2.4 ± 0.3, t=3.333), 5th day (1.0 ± 0.3 vs. 1.6 ± 0.5, t=4.602), 7th day (1.0 ± 0.6 vs. 2.4 ± 0.7, t=6.791), in the treatment group were significantly lower than those in the control group (P<0.01). The remission time of the treatment group was longer than that of the control group on the 1st, 3rd, 5th and 7th day after treatment, but there was no significant difference between the groups (t values were 0.243, 1.374, 0.185, 0.7284, P>0.05). The body function score in the treatment group (88.6 ± 13.7 vs. 77.0 ± 19.4, t=2.184) was significantly higher than that in the control group (P<0.05). Conclusions The combination of traditional Chinese medicine hot-ironing package combined with pushing therapy can alleviate the pain level and improve the quality of life of patients with cancerous abdominal pain.

Umbilical therapy combined with moxibustion for autumn diarrhea in children / 中国针灸

OBJECTIVE@#To observe the efficacy differences between moxibustion combined with umbilical therapy and oral administration of montmorillonite powder (smecta) on diarrhea symptoms in children of different ages.@*METHODS@#A total of 120 children were randomly divided into an observation group and a control group, 60 cases in each group. In the observation group, the children aged under 3 years old were treated with moxibustion at Shenque (CV 8), Zhongwan (CV 12) and Tianshu (ST 25), and each acupoint was treated for less than 3 min, and the total treatment duration was no more than 10 min; the children aged between 3 to 7 years old were treated with moxibustion at Shenque (CV 8), Zhongwan (CV 12), Tianshu (ST 25), Guanyuan (CV 4), Zusanli (ST 36), Pishu (BL 20), Shenshu (BL 23) and Dachangshu (BL 25), each acupoint was treated for less than 3 min, and the total treatment duration was no more than 20 min. After moxibustion, traditional Chinese medicine patch (clove, cinnamon, rhizoma zingiberis, fructus evodiae, hawthorn, rhizoma atractylodis) was applied at Shenque (CV 8). For the children under 1 year old, the medical bag with 30 g powder was heated to 50 ℃ and used for about 30 min; for children over 1 year old, 2-5 g powder was mixed with vinegar and used for 4-8 h each time. The treatment was given once a day, three times as a course of treatment, and a total of one course of treatment was given. The children in the control group were treated with oral administration of montmorillonite powder, 3 g per day for children under 1 year old, 3-6 g per day for children aged 1-2 years old and 6-9 g per day for children over 2 years old. The montmorillonite powder was taken three times a day for 3 days. The diarrhea symptom scores before and after treatment were observed and the clinical efficacy was evaluated. From the first treatment, the recovery cases and recovery time in the two groups were recorded, the recovery cases and recovery time in acute and chronic stages were compared between different age groups. The recurrence was observed 3 months after treatment.@*RESULTS@#Compared before treatment, the diarrhea symptom score after treatment was decreased in the observation group (0.05). After treatment, the score of diarrhea symptoms in the observation group was lower than that in the control group (0.05). The recovery time of different age stages and average recovery time in the observation group were shorter than those in the control group (1 year old and ≤5 years old and average recovery time in the observation group were shorter than those in the control group (<0.05), while the average recovery time of children in chronic stage in the observation group was shorter than that in the control group (<0.05). Three months after treatment, the recurrence rate was 0% (0/36) in acute phase and 4.8% (1/21) in chronic phase in the observation group, which were superior to 9.7% (3/31) in acute phase and 46.7% (7/15) in chronic phase in the control group (<0.05).@*CONCLUSION@#The umbilical therapy combined with moxibustion could improve the symptoms of diarrhea and shorten the recovery time in children of different ages with autumn diarrhea, which have better efficacy than montmorillonite powder.

Umbilical moxibustion for patients with idiopathic pulmonary fibrosis complicated with gastroesophageal reflux of lung-spleen deficiency / 中国针灸

OBJECTIVE@#To evaluate the clinical efficacy of umbilical moxibustion in the treatment of patients with idiopathic pulmonary interstitial fibrosis complicated with gastroesophageal reflux of lung-spleen deficiency.@*METHODS@#A total of 116 patients with idiopathic pulmonary fibrosis complicated with gastroesophageal reflux of lung spleen-deficiency were randomized into an observation group (58 cases) and a control group (58 cases). In the control group, the routine treatment was applied; in the observation group, on the base of the treatment as the control group, the umbilical moxibustion was used. The treatment was given 2 times a week, 2 h each time for 12 weeks, and followed up for 12 weeks after treatment. The composite physiological indicators (CPI), TCM syndrome scores, the St. George respiratory questionnaire score (SGRQ) and 6-minute walk test (6MWT) were compared before and after treatment in the two groups.@*RESULTS@#The improvement of the TCM syndrome scores (cough, post-activity shortness of breath, fatigue, heartburn, acid reflux), CPI score and 6MWT in the observation group was better than those in the control group (all 0.05). There was no significant difference in the scores of CPI scores and syndromes (cough and fatigue) between the two groups at 12 weeks after treatment (all >0.05). The 6MWT, SGRQ scale scores and syndrome scores (post-activity shortness of breath, acid reflux, heartburn) were better than those in the control group in the follow up (all <0.05).@*CONCLUSION@#Umbilical moxibustion can improve the ventilation and diffusion function of lung in patients with idiopathic pulmonary fibrosis and gastroesophageal reflux of lung-spleen deficiency, reduce clinical symptoms and improve patients' quality of life and activity endurance. And it has long-term effect.

Therapeutic effects on primary dysmenorrhea treated with moxibustion at Shenque (CV 8) and warm needling at Guanyuan (CV 4) and Sanyinjiao (SP 6) / 中国针灸

OBJECTIVE@#To explore the clinical effects on primary dysmenorrhea treated with moxibustion at Shenque (CV 8) and warm needling at Guanyuan (CV 4) and Sanyinjiao (SP 6).@*METHODS@#A total of 120 patients with primary dysmenorrhea were randomized into an observation group and a control group, 60 cases in each one. In the control group, the warm needling technique was used at Guanyuan (CV 4) and Sanyinjiao (SP 6). In the observation group, besides the same treatment as the control group, moxibustion was added at Shenque (CV 8). The treatment was given for 4 menstrual cycles consecutively. Before and after treatment, the score of the severity and the score of the total frequency in the retrospective scale of dysmenorrhea symptoms as well as the score of the visual analog scale (VAS) were recorded and compared in the patients between the two groups. Additionally, the safety of the two therapeutic methods was evaluated.@*RESULTS@#After treatment, the score of severity and the score of total frequency as well as VAS score of menstrual pain were all reduced as compared with those before treatment in the patients of the two groups (all 0.05).@*CONCLUSION@#The combined treatment of moxibustion at Shenque (CV 8) with the warm needling technique at Guanyuan (CV 4) and Sanyinjiao (SP 6) achieves the better clinical effects on primary dysmenorrhea as compared with the simple application of the warm needling technique at Guanyuan (CV 4) and Sanyinjiao (SP 6). This therapy is safety in clinical practice.

Analysis of specificity of Shenque (CV 8) based on vascular biology / 中国针灸

To analyze the structural specificity of Shenque (CV 8) in terms of vascular biology from the three aspects of structure, tissue and molecular anatomies. On structural anatomy Shenque (CV 8) possessed defined vascular structure and was the only acupoint directly affected vascular intima. The basis of the specific therapeutic effects was owing to its relation with vessel and abundant microcirculation. Endothelial cells and microvascular endothelial cells were the tissue basis of the starting of therapeutic specificity. Molecular anatomy involved in the functions of transient receptor potential vanilloid family (TRPV) pathway and neuronal peptide secretion of endothelial cells in the structural function of the point. The "restoringfor collapse" effect of salt-partition moxibustion at Shenque (CV 8) was analyzed based on the local biological specificity of blood vessels. The mechanisms were concluded as effectively targeting the dysfunction of microvascular endothelial cells and acquiring the maximum quantity of moxibustion by repeated warm-heat stimulation. The vascular biological structural features of Shenque (CV 8) may contribute to direct therapeutic effects on endothelial cells by the point.

Impacts on urodynamic parameters and the protein expressions of M2 and M3 receptors of detrusor in the rats of detrusor hyperreflexia treated with ginger-salt-isolated moxibustion at "Shenque" (CV 8) / 中国针灸

<p><b>OBJECTIVE</b>To discuss the effects on detrusor hyperreflexia treated with ginger-salt-isolated moxibustion at "Shenque" (CV 8) and its mechanism.</p><p><b>METHODS</b>Thirty female adult SD rats were selected. The model of detrusor hyperreflexia was prepared with complete spinal transection at T, of which, 20 rats were randomized into a model group (10 rats) and a moxibustion group (10 rats). A sham-operation group (10 rats) was set up for sham-spinal transection. In the moxibustion group, when urine incontinence occurred (about in 2 weeks of modeling), the ginger-salt-isolated moxibustion at "Shenque" (CV 8) was given, 3 moxa cones each time, once a day, continuously for 7 days. After treatment, in each group, the urodynamic parameters were determined, after which, the bladder detrusor was collected. Western blot was used to determine the protein expressions of M2 and M3 receptors.</p><p><b>RESULTS</b>Compared with the sham-operation group, the micturition interval was shortened apparently (<0.01); the maximal bladder pressure was increased apparently (<0.01); the protein expression of M2 receptor in the detrusor was increased significantly (<0.05) and that of M3 receptor had no apparent change (>0.05) in the rats of the model group. Compared with the model group, the micturition interval was longer apparently (<0.01), the maximal bladder pressure was reduced apparently (<0.01), the protein expression of M2 receptor in the detrusor was reduced significantly (<0.05) and that of M3 receptor had no apparent change (>0.05) in the rats of the moxibustion group.Compared with the sham-operation group, the results of the above indicators were not different significantly in the moxibustion group (all>0.05).</p><p><b>CONCLUSIONS</b>The ginger-salt-isolated moxibustion at "Shenque" (CV 8) suppresses the overactive bladder in the rat with spinal transection and its effect mechanism is possibly relevant with reducing the protein expression of detrusor M2 and inhibiting the excessive contraction of the detrusor.</p>

Treatment of Child Diarrhea by Ginger-partitioned Moxibustion plus Tuina: A Report of 52 Cases / 针灸推拿医学（英文版）

Treated 52 cases of child diarrhea with ginger-partitioned moxibustion plus Tuina, after three treatments, all the patients are cured.